Minoxi 2%

Active Ingredients

The active ingredient of Minoxi 2 :

• Minoxidil 2%

Indications

Therapeutic group:

Vasodilators, for local use, to treat hair loss.

Minoxi 2 is intended for scalp hair growth among healthy women aged 18-65 in cases of hereditary-type balding only.

Instructions

Do not swallow; this medicine is intended for external use on the scalp only.

Only use the preparation locally and externally, directly on the scalp.

Consult the attending doctor to confirm that your type of hair loss is suitable for treatment with this preparation.

The usual dosage is generally according to the following instructions:

The maximal amount for treatment is 2 ml per day: 1 ml in the morning and 1 ml in the evening (1 ml = 7 sprays). Allow at least 12 hours between each use.

Frequent use and/or use of a larger amount will not increase hair growth, but may cause more side effects , even those that related to decreased blood pressure, such as: chest pain, dizziness, fainting, rapid heartbeat, swelling of the limbs. If one of these effects occurs, stop use and refer to a doctor immediately. Therefore, be sure to measure the dose by the recommended number of sprays.

Do not exceed the recommended dose.

Be sure to wash your hands immediately after using the preparation.

The hair growth process, like the balding and hair loss process, is prolonged; therefore, use the preparation for at least 4 months in order to assess hair regrowth. If you do not see improvement after a few months, refer to the attending doctor.

Use the preparation on completely dry hair and scalp, at a total amount of 1 ml for the entire balding areas. If possible, begin at the center of the balding area and spread the solution with a clean finger. After application, thoroughly wash your hands and any area that has come into contact with the solution. Avoid dripping Minoxi 2 on the face or on skin areas outside of the balding area. If some of it was accidentally spilled onto an area other than the scalp, wash it well with a lot of water. Make sure not to inhale the spray when spraying on the scalp.

After using Minoxi 2: avoid washing the head for approximately two hours. Do not use a hair dryer to hasten hair drying from the solution. Do not place your head on a pillow for at least one hour after application of the scalp.

There are two ways of spraying Minoxi 2; choose the way that most suits you:

1. With the aid of the original spray nozzle, for treatment of balding areas that are not covered with any hair at all, or on large areas:

a. Remove the transparent plastic cover.

b. Hold the bottle vertically, spray the solution onto the treated area and spread onto the entire desired area, using the tips of the fingers. The total quantity of solution to be used (on all the balding areas together) is no more than 7 sprays.

2. With the aid of the long spray nozzle (included in the pack), for treatment of balding areas partially covered with hair, or on a small area:

a. Remove the transparent plastic cover.

b. Pull off the upper part of the spray nozzle (the part with a hole) and replace it with the long spray nozzle.

c. Hold the bottle vertically, spray the solution onto the treated area and spread onto the entire desired area, using the tips of the fingers. The total quantity of solution to be used (on all the balding areas together) is no more than 7 sprays.

The initial hair growth may look soft and downy, but the hair will eventually grow as normal hair.

Continue the treatment even after the hair starts to grow again.

Continue using twice a day, as per the instructions.

If you do not see an improvement in hair growth after one year of use, stop the treatment.

Avoid exposure of the hair to the sun.

How can you contribute to the success of the treatment?

Only apply the preparation when the scalp and hair are completely dry. Adhere to the treatment as per the instructions.

Cessation of treatment will most likely lead to loss of the hair that has grown and renewal of hair loss within 3-4 months.

Young users and/or users whose balding started a short time ago and/or their area of balding is not extensive, may benefit from better results. If the balding process began many years ago and/or the balding area is extensive, the chances of treatment success are low.

Warnings

Do not use the medicine if:

• You are pregnant or breastfeeding
• You are younger than the age of 18 years or older than 65 years
• You are sensitive (allergic) to the active ingredient or any of the additional ingredients contained in the medicine
• The hair loss you are suffering from is not of hereditary origin
• The reason for the hair loss is unknown, if the hair loss is due to childbirth or if the hair loss is sudden and unexpected
• The hair loss is caused by pharmaceutical treatment you are receiving
• You are completely bald or you have lost all of your body hair
• You suffer from hypertension, even if not treated
• You suffer from any condition that affects the scalp (such as: sunburn, psoriasis, etc.)
• You shave your scalp
• You use various creams, ointments or lotions intended for treatment of scalp problems, such as: dithranol (for treatment of psoriasis), tretinoin (to treat acne or additional skin problems), corticosteroids (anti-inflammatory agents, such as: hydrocortisone, betamethasone), paraffin (petrolatum) - a common ingredient in hair creams
• You have any type of dressing on the scalp
• Your scalp is damaged or unhealthy.

Special warnings regarding use of the medicine:

Consult with your doctor if you are suffering, or have suffered in the past, from impaired function of the heart (including arrhythmias, angina pectoris or chest pain and/or blood circulation problems and/or hypertension), the kidney, the blood system (such as coagulation, etc.).

Make sure, before use of the medicine, that the scalp is healthy and not damaged.

If Minoxi 2 passes into the blood stream, it can cause side effects that arise from low blood pressure, such as: chest pain, rapid heartbeat, fainting, dizziness, swelling of the hands and feet, persistent redness or irritation of the scalp. If you experience any of the side effects listed here, stop using the medicine and refer to a doctor immediately. When using the preparation as instructed, it is highly unlikely that these side effects will occur. The risk increases if the preparation was used on damaged skin (such as psoriasis) or following overdose.

The preparation also contains alcohol (ethanol), which upon contact with the eyes, may cause burning and irritation. Avoid contact with the eyes, mouth, damaged skin and sensitive areas. If such contact is made, rinse with a lot of water.

Avoid inhalation of the spray.

Do not use the medicine if you are pregnant or breath feeding.

The preparation is flammable; therefore, do not smoke near it. Do not light a cigarette or be exposed to fire until the preparation has completely dried.

During the treatment period with this medicine, blood, urine, kidney, heart and respiratory system function tests should be performed. Be alert for changes in your general feeling and health condition. If you are sensitive to any food or medicine, inform the doctor before using the medicine. You should be weighed twice a week; in case of sudden weight gain, refer to the doctor immediately. Patients treated with this medicine who have heart diseases and/or hypertension must be under medical supervision throughout the entire treatment period.

If you are taking or have recently taken other medicines, including nonprescription medications and nutritional supplements, inform your doctor or pharmacist. In particular inform the doctor or the pharmacist if you are taking medicines from the following groups:

• Treatment of hypertension (vasodilators, such as hydralazine) - for fear of increase in their activity.
• Local treatment of the scalp.

Please do not consider this information as an alternative to consulting your physician or pharmacist.

For further information on instructions for use, risks and side effects, please read the patient package insert and consult your doctor or pharmacist.
Read the patient package insert carefully before starting to take any medication.